Recombinant HNP-1 Produced by Escherichia coli Triggers Bacterial Apoptosis and Exhibits Antibacterial Activity against Drug-Resistant Bacteria

Human neutrophil peptide-1 (HNP-1) is a promising antibiotic candidate, but its clinical applications have been hampered by challenges during mass production and an inadequate understanding of its bactericidal mechanisms. In this study, we demonstrated that Escherichia coli expressing full-length pr...

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Detalles Bibliográficos
Autores principales: Xie, Qi, Wang, Yin, Zhang, Mengmeng, Wu, Shujia, Wei, Wei, Xiao, Weidi, Wang, Yihao, Zhao, Jinchao, Liu, Nan, Jin, Yiguang, Wu, Junzhu, Xu, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8754131/
https://www.ncbi.nlm.nih.gov/pubmed/35019682
http://dx.doi.org/10.1128/spectrum.00860-21

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8754131/
https://www.ncbi.nlm.nih.gov/pubmed/35019682
http://dx.doi.org/10.1128/spectrum.00860-21

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