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Development of Droplet Digital PCR-Based Assays to Quantify HIV Proviral and Integrated DNA in Brain Tissues from Viremic Individuals with Encephalitis and Virally Suppressed Aviremic Individuals

Although combination antiretroviral therapy (cART) can suppress the replication of HIV, the virus persists and rebounds when treatment is stopped. To find a cure that can eradicate latent reservoir, a method should be able to quantify the lingering HIV. Unlike other digital PCR technologies, droplet...

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Detalles Bibliográficos
Autores principales: Chung, Hye Kyung, Hattler, Julian B., Narola, Jigna, Babbar, Harita, Cai, Yanhui, Abdel-Mohsen, Mohamed, Kim, Woong-Ki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8754137/
https://www.ncbi.nlm.nih.gov/pubmed/35019681
http://dx.doi.org/10.1128/spectrum.00853-21