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Development of Droplet Digital PCR-Based Assays to Quantify HIV Proviral and Integrated DNA in Brain Tissues from Viremic Individuals with Encephalitis and Virally Suppressed Aviremic Individuals
Although combination antiretroviral therapy (cART) can suppress the replication of HIV, the virus persists and rebounds when treatment is stopped. To find a cure that can eradicate latent reservoir, a method should be able to quantify the lingering HIV. Unlike other digital PCR technologies, droplet...
Autores principales: | Chung, Hye Kyung, Hattler, Julian B., Narola, Jigna, Babbar, Harita, Cai, Yanhui, Abdel-Mohsen, Mohamed, Kim, Woong-Ki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8754137/ https://www.ncbi.nlm.nih.gov/pubmed/35019681 http://dx.doi.org/10.1128/spectrum.00853-21 |
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