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MARCH8 Targets Cytoplasmic Lysine Residues of Various Viral Envelope Glycoproteins
The host transmembrane protein MARCH8 is a RING finger E3 ubiquitin ligase that downregulates various host transmembrane proteins, such as MHC-II. We have recently reported that MARCH8 expression in virus-producing cells impairs viral infectivity by reducing virion incorporation of not only HIV-1 en...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8754143/ https://www.ncbi.nlm.nih.gov/pubmed/35019698 http://dx.doi.org/10.1128/spectrum.00618-21 |