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Distinct transcription kinetics of pluripotent cell states

Mouse embryonic stem cells (mESCs) can adopt naïve, ground, and paused pluripotent states that give rise to unique transcriptomes. Here, we use transient transcriptome sequencing (TT‐seq) to define both coding and non‐coding transcription units (TUs) in these three pluripotent states and combine TT‐...

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Detalles Bibliográficos
Autores principales: Shao, Rui, Kumar, Banushree, Lidschreiber, Katja, Lidschreiber, Michael, Cramer, Patrick, Elsässer, Simon J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8754154/
https://www.ncbi.nlm.nih.gov/pubmed/35020268
http://dx.doi.org/10.15252/msb.202110407