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Structures of Two Human Astrovirus Capsid/Neutralizing Antibody Complexes Reveal Distinct Epitopes and Inhibition of Virus Attachment to Cells

Human astrovirus is an important cause of viral gastroenteritis worldwide. Young children, the elderly, and the immunocompromised are especially at risk for contracting severe disease. However, no vaccines exist to combat human astrovirus infection. Evidence points to the importance of antibodies in...

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Detalles Bibliográficos
Autores principales: Ricemeyer, Lena, Aguilar-Hernández, Nayeli, López, Tomás, Espinosa, Rafaela, Lanning, Sarah, Mukherjee, Santanu, Cuellar, Carolina, López, Susana, Arias, Carlos F., DuBois, Rebecca M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8754201/
https://www.ncbi.nlm.nih.gov/pubmed/34613806
http://dx.doi.org/10.1128/JVI.01415-21