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A QP509L/QP383R-Deleted African Swine Fever Virus Is Highly Attenuated in Swine but Does Not Confer Protection against Parental Virus Challenge

African swine fever (ASF), a devastating infectious disease in swine, severely threatens the global pig farming industry. Disease control has been hampered by the unavailability of vaccines. Here, we report that deletion of the QP509L and QP383R genes (ASFV-ΔQP509L/QP383R) from the highly virulent A...

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Detalles Bibliográficos
Autores principales: Li, Dan, Wu, Panxue, Liu, Huanan, Feng, Tao, Yang, Wenping, Ru, Yi, Li, Pan, Qi, Xiaolan, Shi, Zhengwang, Zheng, Haixue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8754219/
https://www.ncbi.nlm.nih.gov/pubmed/34613824
http://dx.doi.org/10.1128/JVI.01500-21