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The K18-Human ACE2 Transgenic Mouse Model Recapitulates Non-severe and Severe COVID-19 in Response to an Infectious Dose of the SARS-CoV-2 Virus

A comprehensive analysis and characterization of a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection model that mimics non-severe and severe coronavirus disease 2019 (COVID-19) in humans is warranted for understating the virus and developing preventive and therapeutic agents. He...

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Detalles Bibliográficos
Autores principales: Dong, Wenjuan, Mead, Heather, Tian, Lei, Park, Jun-Gyu, Garcia, Juan I., Jaramillo, Sierra, Barr, Tasha, Kollath, Daniel S., Coyne, Vanessa K., Stone, Nathan E., Jones, Ashley, Zhang, Jianying, Li, Aimin, Wang, Li-Shu, Milanes-Yearsley, Martha, Torrelles, Jordi B., Martinez-Sobrido, Luis, Keim, Paul S., Barker, Bridget Marie, Caligiuri, Michael A., Yu, Jianhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8754221/
https://www.ncbi.nlm.nih.gov/pubmed/34668775
http://dx.doi.org/10.1128/JVI.00964-21