Cargando…
The K18-Human ACE2 Transgenic Mouse Model Recapitulates Non-severe and Severe COVID-19 in Response to an Infectious Dose of the SARS-CoV-2 Virus
A comprehensive analysis and characterization of a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection model that mimics non-severe and severe coronavirus disease 2019 (COVID-19) in humans is warranted for understating the virus and developing preventive and therapeutic agents. He...
Autores principales: | Dong, Wenjuan, Mead, Heather, Tian, Lei, Park, Jun-Gyu, Garcia, Juan I., Jaramillo, Sierra, Barr, Tasha, Kollath, Daniel S., Coyne, Vanessa K., Stone, Nathan E., Jones, Ashley, Zhang, Jianying, Li, Aimin, Wang, Li-Shu, Milanes-Yearsley, Martha, Torrelles, Jordi B., Martinez-Sobrido, Luis, Keim, Paul S., Barker, Bridget Marie, Caligiuri, Michael A., Yu, Jianhua |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8754221/ https://www.ncbi.nlm.nih.gov/pubmed/34668775 http://dx.doi.org/10.1128/JVI.00964-21 |
Ejemplares similares
-
Contribution of SARS-CoV-2 Accessory Proteins to Viral Pathogenicity in K18 Human ACE2 Transgenic Mice
por: Silvas, Jesus A., et al.
Publicado: (2021) -
Evaluating Antibody Mediated Protection against Alpha, Beta, and Delta SARS-CoV-2 Variants of Concern in K18-hACE2 Transgenic Mice
por: Wong, Ting Y., et al.
Publicado: (2022) -
SARS-CoV-2 Causes Lung Infection without Severe Disease in Human ACE2 Knock-In Mice
por: Winkler, Emma S., et al.
Publicado: (2022) -
A SARS-CoV-2-Related Virus from Malayan Pangolin Causes Lung Infection without Severe Disease in Human ACE2-Transgenic Mice
por: Liu, Mei-Qin, et al.
Publicado: (2023) -
NS1 Protein Mutation I64T Affects Interferon Responses and Virulence of Circulating H3N2 Human Influenza A Viruses
por: DeDiego, Marta L., et al.
Publicado: (2016)