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Disruption of CRTC1 and CRTC2 in Sim1 cells strongly increases high-fat diet intake in female mice but has a modest impact on male mice
cAMP responsive element binding protein (CREB)-regulated transcription coactivators (CRTCs) regulate gene transcription in response to an increase in intracellular cAMP or Ca(2+) levels. To date, three isoforms of CRTC have been identified in mammals. All CRTCs are widely expressed in various region...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8754333/ https://www.ncbi.nlm.nih.gov/pubmed/35020776 http://dx.doi.org/10.1371/journal.pone.0262577 |