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Disruption of CRTC1 and CRTC2 in Sim1 cells strongly increases high-fat diet intake in female mice but has a modest impact on male mice

cAMP responsive element binding protein (CREB)-regulated transcription coactivators (CRTCs) regulate gene transcription in response to an increase in intracellular cAMP or Ca(2+) levels. To date, three isoforms of CRTC have been identified in mammals. All CRTCs are widely expressed in various region...

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Detalles Bibliográficos
Autores principales: Tanaka, Jin, Ishikawa, Fuka, Jinno, Tomoki, Miyakita, Motoki, Miyamori, Haruka, Sasaki, Tsutomu, Yokokawa, Takumi, Goto, Tsuyoshi, Inoue, Kazuo, Matsumura, Shigenobu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8754333/
https://www.ncbi.nlm.nih.gov/pubmed/35020776
http://dx.doi.org/10.1371/journal.pone.0262577