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Engineered neutrophil-derived exosome-like vesicles for targeted cancer therapy

Neutrophils are the most abundant innate immune cells in human circulation; however, their derived exosomes have been rarely studied for tumor treatment. Here, we reported that exosomes from neutrophils (N-Ex) induce tumor cell apoptosis by delivering cytotoxic proteins and activating caspase signal...

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Detalles Bibliográficos
Autores principales: Zhang, Jiahui, Ji, Cheng, Zhang, Hongbo, Shi, Hui, Mao, Fei, Qian, Hui, Xu, Wenrong, Wang, Dongqing, Pan, Jianming, Fang, Xinjian, Santos, Hélder A., Zhang, Xu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8754405/
https://www.ncbi.nlm.nih.gov/pubmed/35020437
http://dx.doi.org/10.1126/sciadv.abj8207