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pH-dependent 11° F(1)F(O) ATP synthase sub-steps reveal insight into the F(O) torque generating mechanism

Most cellular ATP is made by rotary F(1)F(O) ATP synthases using proton translocation-generated clockwise torque on the F(O) c-ring rotor, while F(1)-ATP hydrolysis can force counterclockwise rotation and proton pumping. The F(O) torque-generating mechanism remains elusive even though the F(O) inter...

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Detalles Bibliográficos
Autores principales: Yanagisawa, Seiga, Frasch, Wayne D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8754430/
https://www.ncbi.nlm.nih.gov/pubmed/34970963
http://dx.doi.org/10.7554/eLife.70016