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pH-dependent 11° F(1)F(O) ATP synthase sub-steps reveal insight into the F(O) torque generating mechanism
Most cellular ATP is made by rotary F(1)F(O) ATP synthases using proton translocation-generated clockwise torque on the F(O) c-ring rotor, while F(1)-ATP hydrolysis can force counterclockwise rotation and proton pumping. The F(O) torque-generating mechanism remains elusive even though the F(O) inter...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8754430/ https://www.ncbi.nlm.nih.gov/pubmed/34970963 http://dx.doi.org/10.7554/eLife.70016 |