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Role of Reactivating Mutant p53 Protein in Suppressing Growth and Metastasis of Triple-Negative Breast Cancer

Tumor suppressor p53 protein (p53) plays a vital role throughout the body to conserve DNA stability and prevent cancer. Normally, wild-type p53 protein (wtp53) is either degraded or bound to a negative regulator and is inactive. When damage to DNA occurs within a cell, p53 protein is induced and cau...

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Detalles Bibliográficos
Autores principales: Berke, Taylor P, Slight, Simon H, Hyder, Salman M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8754468/
https://www.ncbi.nlm.nih.gov/pubmed/35035222
http://dx.doi.org/10.2147/OTT.S342292