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Deep Learning-Assisted Repurposing of Plant Compounds for Treating Vascular Calcification: An In Silico Study with Experimental Validation

BACKGROUND: Vascular calcification (VC) constitutes subclinical vascular burden and increases cardiovascular mortality. Effective therapeutics for VC remains to be procured. We aimed to use a deep learning-based strategy to screen and uncover plant compounds that potentially can be repurposed for ma...

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Detalles Bibliográficos
Autores principales: Chao, Chia-Ter, Tsai, You-Tien, Lee, Wen-Ting, Yeh, Hsiang-Yuan, Chiang, Chih-Kang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8754599/
https://www.ncbi.nlm.nih.gov/pubmed/35035662
http://dx.doi.org/10.1155/2022/4378413