Celastrol Protects against Cerebral Ischemia/Reperfusion Injury in Mice by Inhibiting Glycolysis through Targeting HIF-1α/PDK1 Axis

Cerebral ischemia/reperfusion (I/R) injury is closely related to dysfunctional glucose metabolism. Celastrol is a bioactive compound that has been found to exhibit neuroprotective effects in cerebral ischemia, while whether it can protect against cerebral I/R injury by regulating glycolysis remains...

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Detalles Bibliográficos
Autores principales: Chen, Mengyuan, Liu, Maozhu, Luo, Ying, Cao, Jun, Zeng, Fanning, Yang, Lu, Yang, Junqing, Tao, Tao, Jiang, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8754601/
https://www.ncbi.nlm.nih.gov/pubmed/35035665
http://dx.doi.org/10.1155/2022/7420507

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8754601/
https://www.ncbi.nlm.nih.gov/pubmed/35035665
http://dx.doi.org/10.1155/2022/7420507

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