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Celastrol Protects against Cerebral Ischemia/Reperfusion Injury in Mice by Inhibiting Glycolysis through Targeting HIF-1α/PDK1 Axis

Cerebral ischemia/reperfusion (I/R) injury is closely related to dysfunctional glucose metabolism. Celastrol is a bioactive compound that has been found to exhibit neuroprotective effects in cerebral ischemia, while whether it can protect against cerebral I/R injury by regulating glycolysis remains...

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Detalles Bibliográficos
Autores principales:	Chen, Mengyuan, Liu, Maozhu, Luo, Ying, Cao, Jun, Zeng, Fanning, Yang, Lu, Yang, Junqing, Tao, Tao, Jiang, Yu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8754601/ https://www.ncbi.nlm.nih.gov/pubmed/35035665 http://dx.doi.org/10.1155/2022/7420507

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