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Dynamic 23S rRNA modification ho(5)C2501 benefits Escherichia coli under oxidative stress

Post-transcriptional modifications are added to ribosomal RNAs (rRNAs) to govern ribosome biogenesis and to fine-tune protein biosynthesis. In Escherichia coli and related bacteria, RlhA uniquely catalyzes formation of a 5-hydroxycytidine (ho(5)C) at position 2501 of 23S rRNA. However, the molecular...

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Detalles Bibliográficos
Autores principales: Fasnacht, Michel, Gallo, Stefano, Sharma, Puneet, Himmelstoß, Maximilian, Limbach, Patrick A, Willi, Jessica, Polacek, Norbert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8754641/
https://www.ncbi.nlm.nih.gov/pubmed/34904663
http://dx.doi.org/10.1093/nar/gkab1224