Structural basis of DNA methylation-dependent site selectivity of the Epstein–Barr virus lytic switch protein ZEBRA/Zta/BZLF1

In infected cells, Epstein–Barr virus (EBV) alternates between latency and lytic replication. The viral bZIP transcription factor ZEBRA (Zta, BZLF1) regulates this cycle by binding to two classes of ZEBRA response elements (ZREs): CpG-free motifs resembling the consensus AP-1 site recognized by cell...

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Detalles Bibliográficos
Autores principales: Bernaudat, Florent, Gustems, Montse, Günther, Johannes, Oliva, Mizar F, Buschle, Alexander, Göbel, Christine, Pagniez, Priscilla, Lupo, Julien, Signor, Luca, Müller, Christoph W, Morand, Patrice, Sattler, Michael, Hammerschmidt, Wolfgang, Petosa, Carlo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8754650/
https://www.ncbi.nlm.nih.gov/pubmed/34893887
http://dx.doi.org/10.1093/nar/gkab1183

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8754650/
https://www.ncbi.nlm.nih.gov/pubmed/34893887
http://dx.doi.org/10.1093/nar/gkab1183

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