Inhibition mechanisms of CRISPR-Cas9 by AcrIIA17 and AcrIIA18

Mobile genetic elements such as phages and plasmids have evolved anti-CRISPR proteins (Acrs) to suppress CRISPR-Cas adaptive immune systems. Recently, several phage and non-phage derived Acrs including AcrIIA17 and AcrIIA18 have been reported to inhibit Cas9 through modulation of sgRNA. Here, we sho...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Xiaoshen, Li, Xuzichao, Ma, Yongjian, He, Jiaqi, Liu, Xiang, Yu, Guimei, Yin, Hang, Zhang, Heng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8754659/
https://www.ncbi.nlm.nih.gov/pubmed/34893860
http://dx.doi.org/10.1093/nar/gkab1197

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8754659/
https://www.ncbi.nlm.nih.gov/pubmed/34893860
http://dx.doi.org/10.1093/nar/gkab1197

Ejemplares similares