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HIRA complex presets transcriptional potential through coordinating depositions of the histone variants H3.3 and H2A.Z on the poised genes in mESCs

Histone variants have been implicated in regulating chromatin dynamics and genome functions. Previously, we have shown that histone variant H3.3 actively marks enhancers and cooperates with H2A.Z at promoters to prime the genes into a poised state in mouse embryonic stem cells (mESCs). However, how...

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Detalles Bibliográficos
Autores principales: Yang, Yang, Zhang, Liwei, Xiong, Chaoyang, Chen, Jun, Wang, Li, Wen, Zengqi, Yu, Juan, Chen, Ping, Xu, Yanhui, Jin, Jingji, Cai, Yong, Li, Guohong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8754660/
https://www.ncbi.nlm.nih.gov/pubmed/34893908
http://dx.doi.org/10.1093/nar/gkab1221