Cargando…
HIRA complex presets transcriptional potential through coordinating depositions of the histone variants H3.3 and H2A.Z on the poised genes in mESCs
Histone variants have been implicated in regulating chromatin dynamics and genome functions. Previously, we have shown that histone variant H3.3 actively marks enhancers and cooperates with H2A.Z at promoters to prime the genes into a poised state in mouse embryonic stem cells (mESCs). However, how...
Autores principales: | Yang, Yang, Zhang, Liwei, Xiong, Chaoyang, Chen, Jun, Wang, Li, Wen, Zengqi, Yu, Juan, Chen, Ping, Xu, Yanhui, Jin, Jingji, Cai, Yong, Li, Guohong |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8754660/ https://www.ncbi.nlm.nih.gov/pubmed/34893908 http://dx.doi.org/10.1093/nar/gkab1221 |
Ejemplares similares
-
Histone variant H2A.Z regulates nucleosome unwrapping and CTCF binding in mouse ES cells
por: Wen, Zengqi, et al.
Publicado: (2020) -
N
(6)-Methyladenosine modification of lincRNA 1281 is critically required for mESC differentiation potential
por: Yang, Dandan, et al.
Publicado: (2018) -
Assessing genome-wide dynamic changes in enhancer activity during early mESC differentiation by FAIRE-STARR-seq
por: Glaser, Laura V, et al.
Publicado: (2021) -
H3.Y discriminates between HIRA and DAXX chaperone complexes and reveals unexpected insights into human DAXX-H3.3-H4 binding and deposition requirements
por: Zink, Lisa-Maria, et al.
Publicado: (2017) -
Histone chaperone HIRA deposits histone H3.3 onto foreign viral DNA and contributes to anti-viral intrinsic immunity
por: Rai, Taranjit Singh, et al.
Publicado: (2017)