Type I CRISPR-Cas provides robust immunity but incomplete attenuation of phage-induced cellular stress

During infection, phages manipulate bacteria to redirect metabolism towards viral proliferation. To counteract phages, some bacteria employ CRISPR-Cas systems that provide adaptive immunity. While CRISPR-Cas mechanisms have been studied extensively, their effects on both the phage and the host durin...

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Detalles Bibliográficos
Autores principales: Malone, Lucia M, Hampton, Hannah G, Morgan, Xochitl C, Fineran, Peter C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8754663/
https://www.ncbi.nlm.nih.gov/pubmed/34928385
http://dx.doi.org/10.1093/nar/gkab1210

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8754663/
https://www.ncbi.nlm.nih.gov/pubmed/34928385
http://dx.doi.org/10.1093/nar/gkab1210

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