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Type I CRISPR-Cas provides robust immunity but incomplete attenuation of phage-induced cellular stress
During infection, phages manipulate bacteria to redirect metabolism towards viral proliferation. To counteract phages, some bacteria employ CRISPR-Cas systems that provide adaptive immunity. While CRISPR-Cas mechanisms have been studied extensively, their effects on both the phage and the host durin...
Autores principales: | Malone, Lucia M, Hampton, Hannah G, Morgan, Xochitl C, Fineran, Peter C |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8754663/ https://www.ncbi.nlm.nih.gov/pubmed/34928385 http://dx.doi.org/10.1093/nar/gkab1210 |
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