Recognition of G-quadruplex RNA by a crucial RNA methyltransferase component, METTL14

N6-methyladenosine (m6A) is an important epitranscriptomic chemical modification that is mainly catalyzed by the METTL3/METTL14 RNA methyltransferase heterodimer. Although m6A is found at the consensus sequence of 5′-DRACH-3′ in various transcripts, the mechanism by which METTL3/METTL14 determines i...

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Detalles Bibliográficos
Autores principales: Yoshida, Atsuhiro, Oyoshi, Takanori, Suda, Akiyo, Futaki, Shiroh, Imanishi, Miki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
RNA and RNA-protein complexes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8755082/
https://www.ncbi.nlm.nih.gov/pubmed/34908152
http://dx.doi.org/10.1093/nar/gkab1211

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8755082/
https://www.ncbi.nlm.nih.gov/pubmed/34908152
http://dx.doi.org/10.1093/nar/gkab1211

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