Interferon Regulatory Factors IRF1 and IRF7 Directly Regulate Gene Expression in Bats in Response to Viral Infection

Bat cells and tissue have elevated basal expression levels of antiviral genes commonly associated with interferon alpha (IFNα) signaling. Here, we show Interferon Regulatory Factor 1 (IRF1), 3, and 7 levels are elevated in most bat tissues and that, basally, IRFs contribute to the expression of type...

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Detalles Bibliográficos
Autores principales: Irving, Aaron T., Zhang, Qian, Kong, Pui-San, Luko, Katarina, Rozario, Pritisha, Wen, Ming, Zhu, Feng, Zhou, Peng, Ng, Justin H.J., Sobota, Radoslaw M., Wang, Lin-Fa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Author(s). 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8755441/
https://www.ncbi.nlm.nih.gov/pubmed/33147460
http://dx.doi.org/10.1016/j.celrep.2020.108345

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8755441/
https://www.ncbi.nlm.nih.gov/pubmed/33147460
http://dx.doi.org/10.1016/j.celrep.2020.108345

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