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Estrogen promotes innate immune evasion of Candida albicans through inactivation of the alternative complement system

Candida albicans is a commensal of the urogenital tract and the predominant cause of vulvovaginal candidiasis (VVC). Factors that increase circulatory estrogen levels such as pregnancy, the use of oral contraceptives, and hormone replacement therapy predispose women to VVC, but the reasons for this...

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Detalles Bibliográficos
Autores principales: Kumwenda, Pizga, Cottier, Fabien, Hendry, Alexandra C., Kneafsey, Davey, Keevan, Ben, Gallagher, Hannah, Tsai, Hung-Ji, Hall, Rebecca A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8755443/
https://www.ncbi.nlm.nih.gov/pubmed/34986357
http://dx.doi.org/10.1016/j.celrep.2021.110183