Calcium-dependent ESCRT recruitment and lysosome exocytosis maintain epithelial integrity during Candida albicans invasion

Candida albicans is both a commensal and an opportunistic fungal pathogen. Invading hyphae of C. albicans secrete candidalysin, a pore-forming peptide toxin. To prevent cell death, epithelial cells must protect themselves from direct damage induced by candidalysin and by the mechanical forces exerte...

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Detalles Bibliográficos
Autores principales: Westman, Johannes, Plumb, Jonathan, Licht, Anna, Yang, Mabel, Allert, Stefanie, Naglik, Julian R., Hube, Bernhard, Grinstein, Sergio, Maxson, Michelle E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8755444/
https://www.ncbi.nlm.nih.gov/pubmed/34986345
http://dx.doi.org/10.1016/j.celrep.2021.110187

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8755444/
https://www.ncbi.nlm.nih.gov/pubmed/34986345
http://dx.doi.org/10.1016/j.celrep.2021.110187

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