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Extracellular Domains of Transmembrane Proteins Defy the Expression Level–Evolutionary Rate Anticorrelation

Highly expressed proteins tend to evolve slowly, a trend known as the expression level–rate of evolution (E–R) anticorrelation. Whereas the reasons for this anticorrelation remain unclear, the most influential hypotheses attribute it to highly expressed proteins being subjected to strong selective p...

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Detalles Bibliográficos
Autores principales: Sarkar, Chandra, Alvarez-Ponce, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8755491/
https://www.ncbi.nlm.nih.gov/pubmed/34665250
http://dx.doi.org/10.1093/gbe/evab235