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Extracellular Domains of Transmembrane Proteins Defy the Expression Level–Evolutionary Rate Anticorrelation
Highly expressed proteins tend to evolve slowly, a trend known as the expression level–rate of evolution (E–R) anticorrelation. Whereas the reasons for this anticorrelation remain unclear, the most influential hypotheses attribute it to highly expressed proteins being subjected to strong selective p...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8755491/ https://www.ncbi.nlm.nih.gov/pubmed/34665250 http://dx.doi.org/10.1093/gbe/evab235 |