RNA demethylase ALKBH5 promotes tumorigenesis in multiple myeloma via TRAF1-mediated activation of NF-κB and MAPK signaling pathways

N(6)-methyladenosine (m(6)A), an internal modification in mRNA, plays a critical role in regulating gene expression. Dysregulation of m(6)A modifiers promotes oncogenesis through enzymatic functions that disrupt the balance between the deposition and removal of m(6)A modification on critical transcr...

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Detalles Bibliográficos
Autores principales: Qu, Jianwei, Hou, Yifan, Chen, Qingxiao, Chen, Jing, Li, Yi, Zhang, Enfan, Gu, Huiyao, Xu, Ruyi, Liu, Yang, Cao, Wen, Zhang, Jinna, Cao, Liqin, He, Jingsong, Cai, Zhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8755544/
https://www.ncbi.nlm.nih.gov/pubmed/34759347
http://dx.doi.org/10.1038/s41388-021-02095-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8755544/
https://www.ncbi.nlm.nih.gov/pubmed/34759347
http://dx.doi.org/10.1038/s41388-021-02095-8

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