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Very low levels of remdesivir resistance in SARS-COV-2 genomes after 18 months of massive usage during the COVID19 pandemic: A GISAID exploratory analysis

Massive usage of antiviral compounds during a pandemic creates an ideal ground for emergence of resistant strains. Remdesivir, a broad-spectrum inhibitor of the viral RNA-dependent RNA polymerase (RdRp), was extensively prescribed under emergency use authorization during the first 18 months of the C...

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Detalles Bibliográficos
Autores principales: Focosi, Daniele, Maggi, Fabrizio, McConnell, Scott, Casadevall, Arturo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8755559/
https://www.ncbi.nlm.nih.gov/pubmed/35033572
http://dx.doi.org/10.1016/j.antiviral.2022.105247