Synthesis and antiplasmodial activity of regioisomers and epimers of second-generation dual acting ivermectin hybrids

With its strong effect on vector-borne diseases, and insecticidal effect on mosquito vectors of malaria, inhibition of sporogonic and blood-stage development of Plasmodium falciparum, as well as in vitro and in vivo impairment of the P. berghei development inside hepatocytes, ivermectin (IVM) contin...

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Detalles Bibliográficos
Autores principales: Singh, Lovepreet, Fontinha, Diana, Francisco, Denise, Prudêncio, Miguel, Singh, Kamaljit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8755717/
https://www.ncbi.nlm.nih.gov/pubmed/35022455
http://dx.doi.org/10.1038/s41598-021-04532-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8755717/
https://www.ncbi.nlm.nih.gov/pubmed/35022455
http://dx.doi.org/10.1038/s41598-021-04532-w

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