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Single particle cryo-EM structure of the outer hair cell motor protein prestin

The mammalian outer hair cell (OHC) protein prestin (Slc26a5) differs from other Slc26 family members due to its unique piezoelectric-like property that drives OHC electromotility, the putative mechanism for cochlear amplification. Here, we use cryo-electron microscopy to determine prestin’s structu...

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Detalles Bibliográficos
Autores principales: Butan, Carmen, Song, Qiang, Bai, Jun-Ping, Tan, Winston J. T., Navaratnam, Dhasakumar, Santos-Sacchi, Joseph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8755724/
https://www.ncbi.nlm.nih.gov/pubmed/35022426
http://dx.doi.org/10.1038/s41467-021-27915-z