SERPINB3 (SCCA1) inhibits cathepsin L and lysoptosis, protecting cervical cancer cells from chemoradiation

The endogenous lysosomal cysteine protease inhibitor SERPINB3 (squamous cell carcinoma antigen 1, SCCA1) is elevated in patients with cervical cancer and other malignancies. High serum SERPINB3 is prognostic for recurrence and death following chemoradiation therapy. Cervical cancer cells genetically...

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Detalles Bibliográficos
Autores principales: Wang, Songyan, Luke, Cliff J., Pak, Stephen C., Shi, Victoria, Chen, Liyun, Moore, Jonathan, Andress, Arlise P., Jayachandran, Kay, Zhang, Jin, Huang, Yi, Platik, Marina, Apicelli, Anthony A., Schwarz, Julie K., Grigsby, Perry W., Silverman, Gary A., Markovina, Stephanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8755728/
https://www.ncbi.nlm.nih.gov/pubmed/35022555
http://dx.doi.org/10.1038/s42003-021-02893-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8755728/
https://www.ncbi.nlm.nih.gov/pubmed/35022555
http://dx.doi.org/10.1038/s42003-021-02893-6

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