SMYD2 targets RIPK1 and restricts TNF-induced apoptosis and necroptosis to support colon tumor growth

SMYD2 is a histone methyltransferase, which methylates both histone H3K4 as well as a number of non-histone proteins. Dysregulation of SMYD2 has been associated with several diseases including cancer. In the present study, we investigated whether and how SMYD2 might contribute to colorectal cancer....

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Detalles Bibliográficos
Autores principales: Yu, Yu-qiang, Thonn, Veronika, Patankar, Jay V., Thoma, Oana-Maria, Waldner, Maximilian, Zielinska, Marta, Bao, Li-li, Gonzalez-Acera, Miguel, Wallmüller, Stefan, Engel, Felix B., Stürzl, Michael, Neurath, Markus F., Liebing, Eva, Becker, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8755774/
https://www.ncbi.nlm.nih.gov/pubmed/35022391
http://dx.doi.org/10.1038/s41419-021-04483-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8755774/
https://www.ncbi.nlm.nih.gov/pubmed/35022391
http://dx.doi.org/10.1038/s41419-021-04483-0

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