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Structural basis of prokaryotic ubiquitin-like protein engagement and translocation by the mycobacterial Mpa-proteasome complex

Proteasomes are present in eukaryotes, archaea and Actinobacteria, including the human pathogen Mycobacterium tuberculosis, where proteasomal degradation supports persistence inside the host. In mycobacteria and other members of Actinobacteria, prokaryotic ubiquitin-like protein (Pup) serves as a de...

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Detalles Bibliográficos
Autores principales: Kavalchuk, Mikhail, Jomaa, Ahmad, Müller, Andreas U., Weber-Ban, Eilika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8755798/
https://www.ncbi.nlm.nih.gov/pubmed/35022401
http://dx.doi.org/10.1038/s41467-021-27787-3