Cargando…
Structural basis of prokaryotic ubiquitin-like protein engagement and translocation by the mycobacterial Mpa-proteasome complex
Proteasomes are present in eukaryotes, archaea and Actinobacteria, including the human pathogen Mycobacterium tuberculosis, where proteasomal degradation supports persistence inside the host. In mycobacteria and other members of Actinobacteria, prokaryotic ubiquitin-like protein (Pup) serves as a de...
Autores principales: | Kavalchuk, Mikhail, Jomaa, Ahmad, Müller, Andreas U., Weber-Ban, Eilika |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8755798/ https://www.ncbi.nlm.nih.gov/pubmed/35022401 http://dx.doi.org/10.1038/s41467-021-27787-3 |
Ejemplares similares
-
The mycobacterial proteasomal ATPase Mpa forms a gapped ring to engage the 20S proteasome
por: Yin, Yanting, et al.
Publicado: (2021) -
Prokaryotic ubiquitin-like protein remains intrinsically disordered when covalently attached to proteasomal target proteins
por: Barandun, Jonas, et al.
Publicado: (2017) -
Structures of prokaryotic ubiquitin-like protein Pup in complex with depupylase Dop reveal the mechanism of catalytic phosphate formation
por: Cui, Hengjun, et al.
Publicado: (2021) -
Bacterial Proteasome Activator Bpa (Rv3780) Is a Novel Ring-Shaped Interactor of the Mycobacterial Proteasome
por: Delley, Cyrille L., et al.
Publicado: (2014) -
The Bacterial Proteasome at the Core of Diverse Degradation Pathways
por: Müller, Andreas U., et al.
Publicado: (2019)