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Risk for opioid misuse in chronic pain patients is associated with endogenous opioid system dysregulation

µ-Opioid receptors (MOR) are a major target of endogenous and exogenous opioids, including opioid pain medications. The µ-opioid neurotransmitter system is heavily implicated in the pathophysiology of chronic pain and opioid use disorder and, as such, central measures of µ-opioid system functioning...

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Detalles Bibliográficos
Autores principales: Ballester, Javier, Baker, Anne K., Martikainen, Ilkka K., Koppelmans, Vincent, Zubieta, Jon-Kar, Love, Tiffany M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8755811/
https://www.ncbi.nlm.nih.gov/pubmed/35022382
http://dx.doi.org/10.1038/s41398-021-01775-z