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Lysoptosis is an evolutionarily conserved cell death pathway moderated by intracellular serpins

Lysosomal membrane permeabilization (LMP) and cathepsin release typifies lysosome-dependent cell death (LDCD). However, LMP occurs in most regulated cell death programs suggesting LDCD is not an independent cell death pathway, but is conscripted to facilitate the final cellular demise by other cell...

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Detalles Bibliográficos
Autores principales: Luke, Cliff J., Markovina, Stephanie, Good, Misty, Wight, Ira E., Thomas, Brian J., Linneman, John M., Lanik, Wyatt E., Koroleva, Olga, Coffman, Maggie R., Miedel, Mark T., Gong, Qingqing, Andress, Arlise, Campos Guerrero, Marlene, Wang, Songyan, Chen, LiYun, Beatty, Wandy L., Hausmann, Kelsey N., White, Frances V., Fitzpatrick, James A. J., Orvedahl, Anthony, Pak, Stephen C., Silverman, Gary A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8755814/
https://www.ncbi.nlm.nih.gov/pubmed/35022507
http://dx.doi.org/10.1038/s42003-021-02953-x