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Lysoptosis is an evolutionarily conserved cell death pathway moderated by intracellular serpins
Lysosomal membrane permeabilization (LMP) and cathepsin release typifies lysosome-dependent cell death (LDCD). However, LMP occurs in most regulated cell death programs suggesting LDCD is not an independent cell death pathway, but is conscripted to facilitate the final cellular demise by other cell...
Autores principales: | Luke, Cliff J., Markovina, Stephanie, Good, Misty, Wight, Ira E., Thomas, Brian J., Linneman, John M., Lanik, Wyatt E., Koroleva, Olga, Coffman, Maggie R., Miedel, Mark T., Gong, Qingqing, Andress, Arlise, Campos Guerrero, Marlene, Wang, Songyan, Chen, LiYun, Beatty, Wandy L., Hausmann, Kelsey N., White, Frances V., Fitzpatrick, James A. J., Orvedahl, Anthony, Pak, Stephen C., Silverman, Gary A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8755814/ https://www.ncbi.nlm.nih.gov/pubmed/35022507 http://dx.doi.org/10.1038/s42003-021-02953-x |
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