Tolerogenic nanoparticles mitigate the formation of anti-drug antibodies against pegylated uricase in patients with hyperuricemia

Biologic drugs have transformed the standard of care for many diseases. However, many biologics induce the formation of anti-drug antibodies (ADAs), which can compromise their safety and efficacy. Preclinical studies demonstrate that biodegradable nanoparticles-encapsulating rapamycin (ImmTOR), but...

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Detalles Bibliográficos
Autores principales: Sands, Earl, Kivitz, Alan, DeHaan, Wesley, Leung, Sheldon S., Johnston, Lloyd, Kishimoto, Takashi Kei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8755849/
https://www.ncbi.nlm.nih.gov/pubmed/35022448
http://dx.doi.org/10.1038/s41467-021-27945-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8755849/
https://www.ncbi.nlm.nih.gov/pubmed/35022448
http://dx.doi.org/10.1038/s41467-021-27945-7

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