Glucose-dependent insulinotropic polypeptide inhibits cardiac hypertrophy and fibrosis in diabetic mice via suppression of TGF-β2

Diabetic cardiomyopathy is associated with an increased risk for heart failure and death in patients with diabetes. We investigated here whether and how GIP attenuated cardiac hypertrophy and fibrosis in diabetic mice with obesity. Diabetic db/db mice at 7 weeks old were infused with vehicle or GIP...

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Detalles Bibliográficos
Autores principales: Hiromura, Munenori, Mori, Yusaku, Terasaki, Michishige, Kushima, Hideki, Saito, Tomomi, Osaka, Naoya, Yashima, Hironori, Ohara, Makoto, Fukui, Tomoyasu, Matsui, Takanori, Yamagishi, Sho-ichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8755933/
https://www.ncbi.nlm.nih.gov/pubmed/35012372
http://dx.doi.org/10.1177/1479164121999034

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8755933/
https://www.ncbi.nlm.nih.gov/pubmed/35012372
http://dx.doi.org/10.1177/1479164121999034

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