Site-Specific DNA Demethylation as a Potential Target for Cancer Epigenetic Therapy

Aberrant promoter DNA hypermethylation is a typical characteristic of cancer and it is often seen in malignancies. Recent studies showed that regulatory cis-elements found up-stream of many tumor suppressor gene promoter CpG island (CGI) attract DNA methyltransferases (DNMT) that hypermethylates and...

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Detalles Bibliográficos
Autor principal: Neja, Sultan Abda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8756105/
https://www.ncbi.nlm.nih.gov/pubmed/35036833
http://dx.doi.org/10.1177/2516865720964808

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8756105/
https://www.ncbi.nlm.nih.gov/pubmed/35036833
http://dx.doi.org/10.1177/2516865720964808

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