Acquired Resistance Mechanism of EGFR Kinase Domain Duplication to EGFR TKIs in Non–Small Cell Lung Cancer

PURPOSE: Epidermal growth factor receptor kinase domain duplication (EGFR-KDD) is a rare and poorly understood oncogenic mutation in non–small cell lung cancer (NSCLC). We aimed to investigate the acquired resistance mechanism of EGFR-KDD against EGFR-TKIs. MATERIALS AND METHODS: We identified EGFR-...

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Detalles Bibliográficos
Autores principales: Lee, Chaelin, Kim, Miso, Kim, Dong-Wan, Kim, Tae Min, Kim, Soyeon, Im, Sun-Wha, Jeon, Yoon Kyung, Keam, Bhumsuk, Ku, Ja-Lok, Heo, Dae Seog
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Cancer Association 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8756122/
https://www.ncbi.nlm.nih.gov/pubmed/33940786
http://dx.doi.org/10.4143/crt.2021.385

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8756122/
https://www.ncbi.nlm.nih.gov/pubmed/33940786
http://dx.doi.org/10.4143/crt.2021.385

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