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Acquired Resistance Mechanism of EGFR Kinase Domain Duplication to EGFR TKIs in Non–Small Cell Lung Cancer

PURPOSE: Epidermal growth factor receptor kinase domain duplication (EGFR-KDD) is a rare and poorly understood oncogenic mutation in non–small cell lung cancer (NSCLC). We aimed to investigate the acquired resistance mechanism of EGFR-KDD against EGFR-TKIs. MATERIALS AND METHODS: We identified EGFR-...

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Detalles Bibliográficos
Autores principales:	Lee, Chaelin, Kim, Miso, Kim, Dong-Wan, Kim, Tae Min, Kim, Soyeon, Im, Sun-Wha, Jeon, Yoon Kyung, Keam, Bhumsuk, Ku, Ja-Lok, Heo, Dae Seog
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Korean Cancer Association 2022
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8756122/ https://www.ncbi.nlm.nih.gov/pubmed/33940786 http://dx.doi.org/10.4143/crt.2021.385

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