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Targeted Liquid Biopsy Using Irradiation to Facilitate the Release of Cell-Free DNA from a Spatially Aimed Tumor Tissue

PURPOSE: We investigated the feasibility of using an anatomically localized, target-enriched liquid biopsy (TLB) in mouse models of lung cancer. MATERIALS AND METHODS: After irradiating xenograft mouse with human lung cancer cell lines, H1299 (NRAS proto-oncogene, GTPase [NRAS] Q61K) and HCC827 (epi...

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Detalles Bibliográficos
Autores principales: Noh, Jae Myoung, Kim, Yeon Jeong, Lee, Ho Yun, Choi, Changhoon, Ahn, Won-Gyun, Lee, Taeseob, Pyo, Hongryull, Park, Jee Hyun, Park, Donghyun, Park, Woong-Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Cancer Association 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8756125/
https://www.ncbi.nlm.nih.gov/pubmed/34044476
http://dx.doi.org/10.4143/crt.2021.151