preciseTAD: a transfer learning framework for 3D domain boundary prediction at base-pair resolution

MOTIVATION: Chromosome conformation capture technologies (Hi-C) revealed extensive DNA folding into discrete 3D domains, such as Topologically Associating Domains and chromatin loops. The correct binding of CTCF and cohesin at domain boundaries is integral in maintaining the proper structure and fun...

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Detalles Bibliográficos
Autores principales: Stilianoudakis, Spiro C, Marshall, Maggie A, Dozmorov, Mikhail G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8756196/
https://www.ncbi.nlm.nih.gov/pubmed/34741515
http://dx.doi.org/10.1093/bioinformatics/btab743

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8756196/
https://www.ncbi.nlm.nih.gov/pubmed/34741515
http://dx.doi.org/10.1093/bioinformatics/btab743

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