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preciseTAD: a transfer learning framework for 3D domain boundary prediction at base-pair resolution
MOTIVATION: Chromosome conformation capture technologies (Hi-C) revealed extensive DNA folding into discrete 3D domains, such as Topologically Associating Domains and chromatin loops. The correct binding of CTCF and cohesin at domain boundaries is integral in maintaining the proper structure and fun...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8756196/ https://www.ncbi.nlm.nih.gov/pubmed/34741515 http://dx.doi.org/10.1093/bioinformatics/btab743 |