MiR-499a-5p promotes 5-FU resistance and the cell proliferation and migration through activating PI3K/Akt signaling by targeting PTEN in pancreatic cancer

BACKGROUND: Pancreatic cancer (PC) can be considered a representative cancer type of the human body. As demonstrated by some studies, microRNA (miR)-499 is dysregulated in various cancer types including PC, for which chemotherapy involving 5-fluorouracil (5-FU) has long been considered the first-lin...

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Detalles Bibliográficos
Autores principales: Ouyang, Liu, Liu, Ren-Dong, Lei, De-Qiao, Shang, Qing-Chao, Li, Hui-Fen, Hu, Xian-Gui, Zheng, Hao, Jin, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8756217/
https://www.ncbi.nlm.nih.gov/pubmed/35071492
http://dx.doi.org/10.21037/atm-21-6556

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8756217/
https://www.ncbi.nlm.nih.gov/pubmed/35071492
http://dx.doi.org/10.21037/atm-21-6556

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